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Women with typical genetic development are usually capable of giving birth from puberty until menopause.

With regard to gender, a woman may also be a person whose sex assignment does not align with their gender identity, In Old English, wīfmann meant "female human", whereas wēr meant "male human".

Because humans inherit mitochondrial DNA only from the mother's ovum, genetic studies of the female line tend to focus on mitochondrial DNA.

Whether or not a child is considered female does not always determine whether or not the child later will identify themselves that way (see gender identity).

The vagina is used in copulation and birthing, although the term vagina is often colloquially and incorrectly used in the English language for the vulva or external female genitalia, which consists of (in addition to the vagina) the labia, the clitoris, and the female urethra.

(For other ways in which men commonly differ physically from women, see man.) During early fetal development, embryos of both sexes appear gender-neutral.

As in cases without two sexes, such as species that reproduce asexually, the gender-neutral appearance is closer to female than to male.

Most women have the karyotype 46, XX, but around one in a thousand will be 47, XXX, and one in 2500 will be 45, X.

This contrasts with the typical male karotype of 46, XY; thus, the X and Y chromosomes are known as female and male, respectively.

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